"Protein phase transitions inside and outside of cells" by Ned Wingreen (Princeton University)

Date: 
Thursday, February 9, 2017 - 4:00pm to 5:00pm
Series: 
Physics and Astronomy Colloquium

Thursdays, 4:00-5:00 pm

1-434 Physics and Astronomy (map)
Reception from 3:30-4:00 p.m.
(unless otherwise posted)

Guest Speaker: Ned Wingreen (Princeton University)

Talk Title:  “Protein phase transitions inside and outside of cells”

Abstract:

Biologists have recently come to appreciate that eukaryotic cells are home to a multiplicity of non-membrane bound compartments, many of which form and dissolve as needed for the cell to function. These dynamical Òliquid dropletsÓ enable many central cellular functions Ð from ribosome assembly, to RNA regulation and storage, to signaling and metabolism. While it is clear that these compartments represent a type of separated phase, what controls their formation, how specific biological components are included or excluded, and how these structures influence physiological and biochemical processes remain largely mysterious. I will discuss recent experiments on phase separated droplets both in vitro and in vivo, and will present theoretical results that highlight a novel Òmagic numberÓ effect relevant to the formation and control of two-component phase separated liquid droplets.

For more information, contact Jay Hauser

We thank the following people for their contributions to the wine fund for the post-colloquium reception:
Prof. Dolores Bozovic, Prof. Mike Cornwall, Prof. Bob Cousins, Prof. Andrea Ghez, Prof. Karoly Holczer, Prof. Eric Hudson, Robert Huff, Prof. Alex Kusenko, Prof. Myank Mehta, Prof. John Miao, Prof. Roberto Peccei, Prof. Claudio Pellegrini, Prof. David Saltzberg, Prof. Jean Turner and Prof. Ben Zuckerman.

Location: 
1-434 PAB